Mama x Holic ~Miwaku no Mama to Ama Ama Kankei~Forum

Hello,

Did you set your Windows to japanese + japanese clock before installing the game (just in case)?
The exe file could be tagged as a threat, please check if there is a notification from your antivirus.
Else, you can try rename the file mamaholic_crk.exe to Start.exe and see if it helps.
Try to run it as admin too, right click on the exe > run as admin.